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Patient support items for Prometrium® (progesterone) 400mg soft vaginal capsules

Find out how you can provide guidance for your patients on the UK’s first and only licensed progesterone treatment for the prevention of miscarriage in women with a history of recurrent miscarriage who present with bleeding in the first trimester.¹ These resources are to be used with your patients who have been prescribed Prometrium.
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Your role in supporting patients

Prescribing Prometrium for eligible women with a history of recurrent miscarriage can help support their pregnancy and may increase the chances of a successful outcome.2,3

By offering this treatment, you’re offering expecting parents online content designed to help reduce anxiety, and promote a more positive mindset during this critical time.

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Support card

Downloadable patient support card so your patients can have easy access to trusted information and guidance.

You can also request hard copies of the patient support card via your local Besins Healthcare Key Account Manager.

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Patient website

For patients prescribed Prometrium, the patient support website delivers essential information about Prometrium in a clear and empathetic way.

The patient website includes: 

  • About Prometrium – information on how progesterone can help reduce miscarriage risk
  • How to use – step-by-step guidance on administration, timing and dosage
  • Possible side effects – common adverse events and how to report them to the relevant health authorities
  • FAQs – answers to common patient concerns, including medication absorption, administration and considerations for sexual activity 

The website is designed to give your patients everything they need to fully understand why they have been prescribed Prometrium, and guide them to other places where they can find support beyond what Prometrium can offer directly. 

However, patients should also be encouraged to read the patient information leaflet that comes with their medicine as this website does not replace the patient information leaflet.

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External support

Alongside information about Prometrium, directing patients to external resources can help them access emotional support, inspiring stories of strength, and practical advice from trusted pregnancy support communities such as Tommy’s and the Miscarriage Association.

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Explore other resources

Educational resources

Need more information? Discover a range of resources on Prometrium.

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Dosing and administration

Looking for advice on initiating Prometrium? Explore the dosing and administration page below.

View

References

  1. Prometrium 400mg soft vaginal capsules Summary of Product Characteristics. Available at:
    https://www.medicines.org.uk/emc/product/16016/smpcAccessed June 2026
  2. Coomarasamy A, et al. Am J Obstet Gynecol 2020; 223(2):167-176.
  3. Devall AJ, et al. Cochrane Database Syst Rev. 2021;4(4):CD013792.
June 2026 | MAT-PROMO-PTM-0101

Adverse event reporting

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Besins Healthcare (UK) Ltd Drug Safety on 0203 862 0920 or Email: drugsafety@besins-healthcare.com

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